Welcome

to the website of Tinnitus Database.


A large multinational cross-sectional and longitudinal database for clinicians and researchers.


About

Tinnitus is a frequent disorder and its treatment is elusive. Many different treatment options have been investigated but most trials provided inconclusive results with some patients responding and many others without any benefit. These results suggest that there exist different forms of tinnitus which differ in their pathophysiology and their response to specific treatments. A challenge for tinnitus treatment and tinnitus research is therefore the identification of the most promising therapy for a specific patient. One approach to address this challenge is the systematic assessment of tinnitus patients in many clinical centers with standardized instruments (e.g., psychoacoustic measures, questionnaires). For this purpose the Tinnitus Research Initiative database has been created, which is further developed and enlarged in the current COST Action TINNET.

  • The Tinnitus Research Initative Patient Database is a large multinational and rapidly growing patient data base project, in which every interested clinician and researcher can participate
  • Participation in the database project enables the clinician to have fast and comprehensive overview about patients’ clinical characteristics and changes under treatment and thus improves the quality of patient management
  • The large multi-national cross-sectional and longitudinal database of tinnitus patients is a unique resource for profiling of tinnitus patients and identification of outcome predictors for various therapeutic approaches.

Facts

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Centers

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Patients

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Data Sets

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Audiometric Assessments

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Tinnitus Matchings

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Tinnitus Questionnaires

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Quality of Life Assessments

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Assessments of Psychological Well-being

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Comorbidity Assessments

Partners

The database was developed by the Tinnitus Research Initiative (TRI) and the Department for Psychiatry and Psychotherapy of the University of Regensburg and the Institute for Databases and Information Systems (DBIS) at the University of Ulm.



Team

Regensburg

Dr. Winfried Schlee

Dr. Winfried Schlee

Department of Psychiatry and Psychotherapy

Susanne Staudinger

Susanne Staudinger

Department of Psychiatry and Psychotherapy

Prof. Dr. Berthold Langguth

Prof. Dr. Berthold Langguth

Department of Psychiatry and Psychotherapy

PD. Dr. Michael Landgrebe

PD. Dr. Michael Landgrebe

Department of Psychiatry and Psychotherapy

Dr. phil. Martin Schecklmann

Dr. phil. Martin Schecklmann

Department of Psychiatry and Psychotherapy

Patrick Neff

Patrick Neff

Multidisciplinary Tinnitus Clinic

Florian Zeman

Florian Zeman

Center for Clinical Studies

Sylvia Dorner-Mitschke

Sylvia Dorner-Mitschke

Department of Psychiatry and Psychotherapy

Sandra Pflügl

Sandra Pflügl

Department of Psychiatry and Psychotherapy

Ulm

Dr. Rüdiger Pryss

Dr. Rüdiger Pryss

Institute of Databases and Information Systems

Prof. Dr. Manfred Reichert

Prof. Dr. Manfred Reichert

Institute of Databases and Information Systems

Michael Stach

Michael Stach

Institute of Databases and Information Systems

Jochen Herrmann

Jochen Herrmann

Developer

Aliyar Aras

Aliyar Aras

Developer

Norman Thiel

Norman Thiel

Developer

Robin Zöller

Robin Zöller

Developer

Marc Schickler

Marc Schickler

Institute of Databases and Information Systems

Johannes Schobel

Johannes Schobel

Institute of Databases and Information Systems

Robin Hagenlocher

Robin Hagenlocher

Designer

Irina Stenske

Irina Stenske

Designer

Burak Baltakiranoglu

Burak Baltakiranoglu

Designer

Andreas Rein

Andreas Rein

Developer

Leyla Ernst

Leyla Ernst

Developer

Jan Musmann

Jan Musmann

Developer

Benjamin Schanzel

Benjamin Schanzel

Developer

Magdeburg

Prof. Dr. Myra Spiliopoulou

Prof. Dr. Myra Spiliopoulou

Department of Technical and Business Information Systems

Sven Kalle

Sven Kalle

Department of Technical and Business Information Systems

Vishnu Unnikrishnan

Vishnu Unnikrishnan

Department of Technical and Business Information Systems

Tommy Hielscher

Tommy Hielscher

Department of Technical and Business Information Systems

Publications

2017

"Report on the Big Data Conference in ENT Clinical Research", Paris IFOS Conference, http://www.lorenzinifoundation.org/big-data-conference-ent-clinical-research, 2017, [Online; accessed 08-January-2018].

Langguth B, Landgrebe M, Schlee W, et al. Different Patterns of Hearing Loss among Tinnitus Patients: A Latent Class Analysis of a Large Sample. Frontiers in Neurology. 2017;8:46. doi:10.3389/fneur.2017.00046.

2016

Vielsmeier, Veronika and Kreuzer, Peter and Haubner, Frank and Steffens, Thomas and Semmler, Philipp and Kleinjung, Tobias and Schlee, Winfried and Langguth, Berthold and Schecklmann, Martin (2016). Speech comprehension difficulties in chronic tinnitus and its relation to hyperacusis. In: Frontiers in Aging Neuroscience. Volume 8, Pages 293. DOI 10.3389/fnagi.2016.00293.

Insomnia in patients with chronic tinnitus: Cognitive and emotional distress as moderator variables. Crönlein T, Langguth B, Pregler M, Kreuzer PM, Wetter TC, Schecklmann M. J Psychosom Res. 2016 Apr;83:65-8. doi: 10.1016/j.jpsychores.2016.03.001.

2015

Tinnitus and Headache. Langguth B, Hund V, Busch V, Jürgens TP, Lainez JM, Landgrebe M, Schecklmann M. Biomed Res Int. 2015;2015:797416. doi: 10.1155/2015/797416.

Psychophysiological Associations between Chronic Tinnitus and Sleep: A Cross Validation of Tinnitus and Insomnia Questionnaires. Schecklmann M, Pregler M, Kreuzer PM, Poeppl TB, Lehner A, Crönlein T, Wetter TC, Frank E, Landgrebe M, Langguth B. Biomed Res Int. 2015;2015:461090. doi: 10.1155/2015/461090.

The Relevance of the High Frequency Audiometry in Tinnitus Patients with Normal Hearing in Conventional Pure-Tone Audiometry. Vielsmeier V, Lehner A, Strutz J, Steffens T, Kreuzer PM, Schecklmann M, Landgrebe M, Langguth B, Kleinjung T. Biomed Res Int. 2015;2015:302515. doi: 10.1155/2015/302515.

Validation of Screening Questions for Hyperacusis in Chronic Tinnitus. Schecklmann M, Lehner A, Schlee W, Vielsmeier V, Landgrebe M, Langguth B. Biomed Res Int. 2015;2015:191479. doi: 10.1155/2015/191479.

2014

Schecklmann, M., Landgrebe, M., Langguth, B., & TRI Database Study Group. (2014). Phenotypic characteristics of hyperacusis in tinnitus. PLoS One, 9(1), e86944.

Zeman, F., Koller, M., Langguth, B., & Landgrebe, M. (2014). Which tinnitus-related aspects are relevant for quality of life and depression: results from a large international multicentre sample. Health and quality of life outcomes, 12(1), 1.

2013

Milerová, J., Anders, M., Dvo?ák, T., Sand, P. G., Königer, S., & Langguth, B. (2013). The influence of psychological factors on tinnitus severity. General hospital psychiatry, 35(4), 412-416.

2012

Landgrebe, M., Azevedo, A., Baguley, D., Bauer, C., Cacace, A., Coelho, C., ... & van de Heyning, P. (2012). Methodological aspects of clinical trials in tinnitus: a proposal for an international standard. Journal of psychosomatic research, 73(2), 112-121.

Schecklmann, M., Vielsmeier, V., Steffens, T., Landgrebe, M., Langguth, B., & Kleinjung, T. (2012). Relationship between audiometric slope and tinnitus pitch in tinnitus patients: insights into the mechanisms of tinnitus generation. PLoS One, 7(4), e34878.

Adamchic, I., Tass, P. A., Langguth, B., Hauptmann, C., Koller, M., Schecklmann, M., ... & Landgrebe, M. (2012). Linking the Tinnitus Questionnaire and the subjective Clinical Global Impression: Which differences are clinically important?. Health and quality of life outcomes, 10(1), 1.

Zeman, F., Koller, M., Schecklmann, M., Langguth, B., & Landgrebe, M. (2012). Tinnitus assessment by means of standardized self-report questionnaires: psychometric properties of the Tinnitus Questionnaire (TQ), the Tinnitus Handicap Inventory (THI), and their short versions in an international and multi-lingual sample. Health and quality of life outcomes, 10(1), 1.

Kreuzer, P. M., Landgrebe, M., Schecklmann, M., Staudinger, S., & Langguth, B. (2012). Trauma-associated tinnitus: audiological, demographic and clinical characteristics. PLoS One, 7(9), e45599.

Coelho, C., Figueiredo, R., Frank, E., Burger, J., Schecklmann, M., Landgrebe, M., ... & Elgoyhen, A. B. (2012). Reduction of tinnitus severity by the centrally acting muscle relaxant cyclobenzaprine: an open-label pilot study. Audiology and Neurotology, 17(3), 179-188.

Schecklmann, M., Lehner, A., Poeppl, T. B., Kreuzer, P. M., Hajak, G., Landgrebe, M., & Langguth, B. (2012). Cluster analysis for identifying sub-types of tinnitus: a positron emission tomography and voxel-based morphometry study. Brain research, 1485, 3-9.

2011

Zeman, F., Koller, M., Figueiredo, R., Aazevedo, A., Rates, M., Coelho, C., ... & Landgrebe, M. (2011). Tinnitus Handicap Inventory for Evaluating Treatment Effects Which Changes Are Clinically Relevant?. Otolaryngology--Head and Neck Surgery, 145(2), 282-287.

Langguth, B., Kleinjung, T., & Landgrebe, M. (2011). Tinnitus: the complexity of standardization. Evaluation & the health professions, 0163278710394337.

Langguth, B., Kleinjung, T., & Landgrebe, M. (2011). Severe tinnitus and depressive symptoms: a complex interaction. Otolaryngology--Head and Neck Surgery, 145(3), 519-519.

2010

Landgrebe, M., Zeman, F., Koller, M., Eberl, Y., Mohr, M., Reiter, J., ... & Langguth, B. (2010). The Tinnitus Research Initiative (TRI) database: a new approach for delineation of tinnitus subtypes and generation of predictors for treatment outcome. BMC medical informatics and decision making, 10(1), 1.

2007

Langguth, B., Goodey, R., Azevedo, A., Bjorne, A., Cacace, A., Crocetti, A., ... & Flor, H. (2007). Consensus for tinnitus patient assessment and treatment outcome measurement: Tinnitus Research Initiative meeting, Regensburg, July 2006. Progress in brain research, 166, 525-536.

Contact

If you have questions, feedback or suggestions please don't hesitate to contact us under the following adress or mail.


Susanne Staudinger

medbo - Bezirksklinikum Regensburg
Universitätsstrasse 84
93053 Regensburg

susanne.staudingermedbo.de