Welcome

to the website of Tinnitus Database.


A large multinational cross-sectional and longitudinal database for clinicians and researchers.
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About

Tinnitus is a frequent disorder and its treatment is elusive. Many different treatment options have been investigated but most trials provided inconclusive results with some patients responding and many others without any benefit. These results suggest that there exist different forms of tinnitus which differ in their pathophysiology and their response to specific treatments. A challenge for tinnitus treatment and tinnitus research is therefore the identification of the most promising therapy for a specific patient. One approach to address this challenge is the systematic assessment of tinnitus patients in many clinical centers with standardized instruments (e.g., psychoacoustic measures, questionnaires). For this purpose the Tinnitus Research Initiative database has been created, which is further developed and enlarged in the current COST Action TINNET.

  • The Tinnitus Research Initative Patient Database is a large multinational and rapidly growing patient data base project, in which every interested clinician and researcher can participate
  • Participation in the database project enables the clinician to have fast and comprehensive overview about patients’ clinical characteristics and changes under treatment and thus improves the quality of patient management
  • The large multi-national cross-sectional and longitudinal database of tinnitus patients is a unique resource for profiling of tinnitus patients and identification of outcome predictors for various therapeutic approaches.

Features

Facts

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Centers

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Patients

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Data Sets

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Audiometric Assessments

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Tinnitus Matchings

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Tinnitus Questionnaires

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Quality of Life Assessments

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Assessments of Psychological Well-being

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Comorbidity Assessments

Partners

The database was developed by the Tinnitus Research Initiative (TRI) and the Department for Psychiatry and Psychotherapy of the University of Regensburg and the Institute for Databases and Information Systems (DBIS) at the University of Ulm.



Team

Regensburg

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Dr. Winfried Schlee

University of Regensburg

Department of Psychiatry and Psychotherapy

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Susanne Staudinger

University of Regensburg

Department of Psychiatry and Psychotherapy

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Prof. Dr. Berthold Langguth

University of Regensburg

Department of Psychiatry and Psychotherapy

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PD. Dr. Michael Landgrebe

University of Regensburg

Department of Psychiatry and Psychotherapy

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Dr. phil. Martin Schecklmann

University of Regensburg

Department of Psychiatry and Psychotherapy

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Florian Zeman

University Hospital Regensburg

Center for Clinical Studies

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Sylvia Dorner-Mitschke

University of Regensburg

Department of Psychiatry and Psychotherapy

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Sandra Pflügl

University of Regensburg

Department of Psychiatry and Psychotherapy


Ulm

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Dr. Rüdiger Pryss

Ulm University

Institute of Databases and Information Systems

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Prof. Dr. Manfred Reichert

Ulm University

Institute of Databases and Information Systems

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Michael Stach

Ulm University

Institute of Databases and Information Systems

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Jochen Herrmann

Ulm University

Developer

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Aliyar Aras

Ulm University

Developer

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Norman Thiel

Ulm University

Developer

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Robin Zöller

Ulm University

Developer

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Marc Schickler

Ulm University

Institute of Databases and Information Systems

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Johannes Schobel

Ulm University

Institute of Databases and Information Systems

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Robin Hagenlocher

Ulm University

Designer

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Irina Stenske

Ulm University

Designer

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Burak Baltakiranoglu

Ulm University

Designer

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Andreas Rein

Ulm University

Developer

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Leyla Ernst

Ulm University

Developer

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Jan Musmann

Ulm University

Developer


Magdeburg

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Prof. Dr. Myra Spiliopoulou

Otto-von-Guericke-University Magdeburg

Department of Technical and Business Information Systems

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Sven Kalle

Otto-von-Guericke-University Magdeburg

Department of Technical and Business Information Systems

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Vishnu Unnikrishnan

Otto-von-Guericke-University Magdeburg

Department of Technical and Business Information Systems

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Tommy Hielscher

Otto-von-Guericke-University Magdeburg

Department of Technical and Business Information Systems

Publications

2017

Langguth B, Landgrebe M, Schlee W, et al. Different Patterns of Hearing Loss among Tinnitus Patients: A Latent Class Analysis of a Large Sample. Frontiers in Neurology. 2017;8:46. doi:10.3389/fneur.2017.00046.

2016

Vielsmeier, Veronika and Kreuzer, Peter and Haubner, Frank and Steffens, Thomas and Semmler, Philipp and Kleinjung, Tobias and Schlee, Winfried and Langguth, Berthold and Schecklmann, Martin (2016). Speech comprehension difficulties in chronic tinnitus and its relation to hyperacusis. In: Frontiers in Aging Neuroscience. Volume 8, Pages 293. DOI 10.3389/fnagi.2016.00293.

Insomnia in patients with chronic tinnitus: Cognitive and emotional distress as moderator variables. Crönlein T, Langguth B, Pregler M, Kreuzer PM, Wetter TC, Schecklmann M. J Psychosom Res. 2016 Apr;83:65-8. doi: 10.1016/j.jpsychores.2016.03.001.

2015

Tinnitus and Headache. Langguth B, Hund V, Busch V, Jürgens TP, Lainez JM, Landgrebe M, Schecklmann M. Biomed Res Int. 2015;2015:797416. doi: 10.1155/2015/797416.

Psychophysiological Associations between Chronic Tinnitus and Sleep: A Cross Validation of Tinnitus and Insomnia Questionnaires. Schecklmann M, Pregler M, Kreuzer PM, Poeppl TB, Lehner A, Crönlein T, Wetter TC, Frank E, Landgrebe M, Langguth B. Biomed Res Int. 2015;2015:461090. doi: 10.1155/2015/461090.

The Relevance of the High Frequency Audiometry in Tinnitus Patients with Normal Hearing in Conventional Pure-Tone Audiometry. Vielsmeier V, Lehner A, Strutz J, Steffens T, Kreuzer PM, Schecklmann M, Landgrebe M, Langguth B, Kleinjung T. Biomed Res Int. 2015;2015:302515. doi: 10.1155/2015/302515.

Validation of Screening Questions for Hyperacusis in Chronic Tinnitus. Schecklmann M, Lehner A, Schlee W, Vielsmeier V, Landgrebe M, Langguth B. Biomed Res Int. 2015;2015:191479. doi: 10.1155/2015/191479.

2014

Schecklmann, M., Landgrebe, M., Langguth, B., & TRI Database Study Group. (2014). Phenotypic characteristics of hyperacusis in tinnitus. PLoS One, 9(1), e86944.

Zeman, F., Koller, M., Langguth, B., & Landgrebe, M. (2014). Which tinnitus-related aspects are relevant for quality of life and depression: results from a large international multicentre sample. Health and quality of life outcomes, 12(1), 1.

2013

Milerová, J., Anders, M., Dvo?ák, T., Sand, P. G., Königer, S., & Langguth, B. (2013). The influence of psychological factors on tinnitus severity. General hospital psychiatry, 35(4), 412-416.

2012

Landgrebe, M., Azevedo, A., Baguley, D., Bauer, C., Cacace, A., Coelho, C., ... & van de Heyning, P. (2012). Methodological aspects of clinical trials in tinnitus: a proposal for an international standard. Journal of psychosomatic research, 73(2), 112-121.

Schecklmann, M., Vielsmeier, V., Steffens, T., Landgrebe, M., Langguth, B., & Kleinjung, T. (2012). Relationship between audiometric slope and tinnitus pitch in tinnitus patients: insights into the mechanisms of tinnitus generation. PLoS One, 7(4), e34878.

Adamchic, I., Tass, P. A., Langguth, B., Hauptmann, C., Koller, M., Schecklmann, M., ... & Landgrebe, M. (2012). Linking the Tinnitus Questionnaire and the subjective Clinical Global Impression: Which differences are clinically important?. Health and quality of life outcomes, 10(1), 1.

Zeman, F., Koller, M., Schecklmann, M., Langguth, B., & Landgrebe, M. (2012). Tinnitus assessment by means of standardized self-report questionnaires: psychometric properties of the Tinnitus Questionnaire (TQ), the Tinnitus Handicap Inventory (THI), and their short versions in an international and multi-lingual sample. Health and quality of life outcomes, 10(1), 1.

Kreuzer, P. M., Landgrebe, M., Schecklmann, M., Staudinger, S., & Langguth, B. (2012). Trauma-associated tinnitus: audiological, demographic and clinical characteristics. PLoS One, 7(9), e45599.

Coelho, C., Figueiredo, R., Frank, E., Burger, J., Schecklmann, M., Landgrebe, M., ... & Elgoyhen, A. B. (2012). Reduction of tinnitus severity by the centrally acting muscle relaxant cyclobenzaprine: an open-label pilot study. Audiology and Neurotology, 17(3), 179-188.

Schecklmann, M., Lehner, A., Poeppl, T. B., Kreuzer, P. M., Hajak, G., Landgrebe, M., & Langguth, B. (2012). Cluster analysis for identifying sub-types of tinnitus: a positron emission tomography and voxel-based morphometry study. Brain research, 1485, 3-9.

2011

Zeman, F., Koller, M., Figueiredo, R., Aazevedo, A., Rates, M., Coelho, C., ... & Landgrebe, M. (2011). Tinnitus Handicap Inventory for Evaluating Treatment Effects Which Changes Are Clinically Relevant?. Otolaryngology--Head and Neck Surgery, 145(2), 282-287.

Langguth, B., Kleinjung, T., & Landgrebe, M. (2011). Tinnitus: the complexity of standardization. Evaluation & the health professions, 0163278710394337.

Langguth, B., Kleinjung, T., & Landgrebe, M. (2011). Severe tinnitus and depressive symptoms: a complex interaction. Otolaryngology--Head and Neck Surgery, 145(3), 519-519.

2010

Landgrebe, M., Zeman, F., Koller, M., Eberl, Y., Mohr, M., Reiter, J., ... & Langguth, B. (2010). The Tinnitus Research Initiative (TRI) database: a new approach for delineation of tinnitus subtypes and generation of predictors for treatment outcome. BMC medical informatics and decision making, 10(1), 1.

2007

Langguth, B., Goodey, R., Azevedo, A., Bjorne, A., Cacace, A., Crocetti, A., ... & Flor, H. (2007). Consensus for tinnitus patient assessment and treatment outcome measurement: Tinnitus Research Initiative meeting, Regensburg, July 2006. Progress in brain research, 166, 525-536.

Contact

If you have questions, feedback or suggestions please don't hesitate to contact us under the following adress or mail.


Susanne Staudinger

  

medbo - Bezirksklinikum Regensburg

Universitätsstrasse 84

93053 Regensburg

  Susanne.Staudinger[at]medbo.de